Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.38 |
| ▸ | TPH1 | P17752 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23386596 | 0.92 | SLC6A15 (0.39) | SLC6A15MRGPRX4TPH1CNR2KDM4C | |
| SCHEMBL23386591 | 0.83 | SLC6A15 (0.40) | SLC6A15MRGPRX4TPH1CNR2KDM4C | |
| SCHEMBL25643128 | 0.79 | S1PR4 (0.36) | S1PR4KDM1A | |
| SCHEMBL26314795 | 0.77 | KDM1A (0.38) | KDM4CPPARGPPARDPPARASMN1; SMN2 | |
| SCHEMBL26194442 | 0.75 | LMNA (0.39) | S1PR4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26314917 | 0.75 | HCAR3 (0.39) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23442629 | 0.74 | USP2 (0.38) | MRGPRX4KDM4CHDAC3HDAC1HDAC2 | |
| SCHEMBL20523241 | 0.74 | SLC6A15 (0.41) | SLC6A15MRGPRX4TPH1KDM4CS1PR4 | |
| SCHEMBL20523238 | 0.74 | SLC6A15 (0.41) | SLC6A15MRGPRX4TPH1KDM4CS1PR4 | |
| SCHEMBL17565610 | 0.74 | KDM1A (0.43) | KDM4CKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667652-B2 | MCL1 inhibitors | GILEAD SCIENCES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667652-B2 | MCL1 inhibitors | MCL1, BCL2L1, BCLAF1 | SLC6A15 4775/4885MRGPRX4 3632/4885TPH1 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.