Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2566812 | 0.76 | CA2 (0.40) | CA2 | |
| SCHEMBL766824 | 0.68 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL774246 | 0.67 | — | — | |
| SCHEMBL2564326 | 0.67 | CHRNB2 (0.38) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL767372 | 0.66 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL14106336 | 0.64 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL8279470 | 0.64 | — | — | |
| SCHEMBL16965084 | 0.62 | CHRNB2 (0.71) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL2965145 | 0.62 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL8788169 | 0.62 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382227-A1 | SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS | Girindus America, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010072831-A1 | SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS | GIRINDUS AMERICA, INC (US) | 2010-07-01 | — | — | WO | disclosed |