Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544332 | 0.85 | GAA (0.57) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL9033161 | 0.83 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL9784216 | 0.81 | CYP1A2 (0.41) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL1845681 | 0.79 | HTT (0.41) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL23768567 | 0.78 | CYP2C9 (0.40) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL5963274 | 0.77 | CYP2D6 (0.55) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL27081029 | 0.77 | GAA (0.54) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL4029374 | 0.77 | GAA (0.48) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL223549 | 0.77 | GAA (0.68) | CYP1A2CYP2C9CYP2C19HTTGAA | |
| SCHEMBL14822738 | 0.77 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11679158-B2 | Biodegradable lipids for the delivery of active agents | LIPA, APOB, CETP | CYP1A2 4252/4885CYP2C9 4460/4885CYP2C19 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.