Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544332 | 0.91 | GAA (0.57) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL27081029 | 0.82 | GAA (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL5963274 | 0.82 | CYP2D6 (0.55) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1359006 | 0.81 | — | — | |
| SCHEMBL20841661 | 0.81 | MGAM (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8503864 | 0.81 | TSHR (0.49) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10749891 | 0.80 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7527314 | 0.79 | MGAM (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1927747 | 0.79 | — | — | |
| SCHEMBL17193285 | 0.78 | CES2 (0.44) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687301-B1 | THIAEPOTHILONE FOR TREATING CANCEROUS DISEASES | LEIBNIZ INST FUER PFLANZENBIOC (DE) | 2009-05-13 | — | — | EP | claimed |
| US-8461355-B2 | Preparation method of 3,4-ethylenedioxythiophene | FAR EASTERN NEW CENTURY CORPORATION (TW) | 2013-06-11 | — | — | US | disclosed |
| US-20130023673-A1 | Preparation Method of 3,4-Ethylenedioxythiophene | FAR EASTERN NEW CENTURY CORPORATION (TW) | 2013-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023673-A1 | Preparation Method of 3,4-Ethylenedioxythiophene | DNTT, CCNT1, NUDT1 | GAA 4145/4885MGAM 1751/4885SI 1601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.