Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 19/20 | 0.57 |
| ▸ | WNT1 | P04628 | 14/20 | 0.57 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | CLK3 | P49761 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19662951 | 0.84 | PIM1 (0.53) | — | |
| SCHEMBL25603068 | 0.83 | GSK3B (0.56) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL20945222 | 0.83 | GSK3B (0.56) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL15507418 | 0.83 | GSK3B (0.56) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL30481240 | 0.83 | GSK3B (0.56) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL30381685 | 0.83 | GSK3B (0.56) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL23762167 | 0.82 | CYP11B1 (0.47) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL23048755 | 0.82 | DYRK1A (0.56) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL19546567 | 0.81 | GSK3B (0.67) | GSK3BDYRK1AWNT1CLK2CLK3 | |
| SCHEMBL25646448 | 0.81 | GSK3B (0.54) | GSK3BDYRK1AWNT1CLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107722-A1 | COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |