SCHEMBL25646901

SCHEMBL25646901

c1cnnc(N2CC3CCC2CN3)c1

nearest known ligand 0.76

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 4/20 0.57
CHRNA4 P43681 4/20 0.57
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
HDAC1 Q13547 1/20 0.41
GRM2 Q14416 1/20 0.41
IRAK4 Q9NWZ3 2/20 0.38
ROCK2 O75116 1/20 0.37
GLS O94925 1/20 0.37
HTR1D P28221 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5041484 0.86 CHRNB2 (0.56) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL5385567 0.86 CHRNB2 (0.56) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL5043529 0.78 CHRNB2 (0.54) CHRNB2CHRNA4CHRNB4CHRNA3HDAC1
SCHEMBL5034067 0.73 CHRNB2 (1.00) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL5375565 0.73 CHRNB2 (1.00) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL5374487 0.73 CHRNB2 (1.00) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL19839760 0.72 CHRNB2 (0.69) CHRNB2CHRNA4CHRNB4CHRNA3HDAC1
SCHEMBL19852080 0.72 CHRNB2 (0.69) CHRNB2CHRNA4CHRNB4CHRNA3HDAC1
Hydrochloric Acid SCHEMBL5036862 0.72 CHRNB2 (0.97) CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL22769058 0.71 CHRNB2 (0.46) CHRNB2CHRNA4GRM2IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023104155-A1 LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF 标新生物医药科技(上海)有限公司 2023-06-15 WO disclosed