Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034127 | 0.87 | CHRNB2 (0.61) | CHRNB2CHRNA4 | |
| SCHEMBL6625406 | 0.87 | CHRNB2 (0.61) | CHRNB2CHRNA4 | |
| SCHEMBL2963520 | 0.87 | CHRNB2 (0.61) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7250231 | 0.85 | CHRNB2 (0.59) | CHRNB2CHRNA4 | |
| SCHEMBL25646901 | 0.78 | CHRNB2 (0.57) | CHRNB2CHRNA4CHRNB4CHRNA3HDAC1 | |
| SCHEMBL5377778 | 0.75 | CHRNB2 (0.79) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5038459 | 0.75 | CHRNB2 (0.79) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL7687469 | 0.75 | CHRNB2 (0.68) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL7241098 | 0.72 | CHRNB2 (0.57) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL5034061 | 0.72 | CHRNB2 (0.45) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359152-B1 | Diazabicyclic derivatives as nicotinic acetylcholine receptor ligands | ABBOTT LAB (US) | 2008-05-07 | — | — | EP | claimed |