Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.68 |
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1075098 | 0.81 | AR (1.00) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL12955524 | 0.81 | AR (1.00) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL12955359 | 0.81 | AR (1.00) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL12955377 | 0.81 | AR (0.68) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL1076493 | 0.78 | AR (1.00) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL28018259 | 0.78 | AR (0.63) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL863462 | 0.77 | AR (1.00) | ARPARP1LMNAPRMT5TSHR | |
| SCHEMBL21575704 | 0.76 | PRMT5 (0.68) | ARPARP1LMNAPRMT5TSHR | |
| SCHEMBL19748630 | 0.76 | AR (0.68) | ARPARP1LMNAHTTNPSR1 | |
| SCHEMBL29655147 | 0.76 | AR (0.68) | ARPARP1LMNAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |