Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 1.00 |
| ▸ | PARP1 | P09874 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.64 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28018258 | 0.92 | PARP1 (0.85) | ARPARP1LMNAPRMT5ENPP1 | |
| SCHEMBL905630 | 0.88 | AR (0.79) | ARPARP1LMNAPRMT5ENPP1 | |
| SCHEMBL29349943 | 0.87 | LMNA (1.00) | ARPARP1LMNAPRMT5ENPP1 | |
| SCHEMBL1789242 | 0.87 | LMNA (1.00) | ARPARP1LMNAPRMT5ENPP1 | |
| SCHEMBL12955544 | 0.87 | AR (0.77) | ARPARP1LMNAPRMT5ENPP1 | |
| SCHEMBL7122967 | 0.87 | AR (0.77) | ARPARP1LMNAPRMT5ENPP1 | |
| SCHEMBL8154178 | 0.87 | AR (0.77) | ARPARP1LMNAPRMT5ENPP1 | |
| SCHEMBL12955341 | 0.87 | AR (0.77) | ARPARP1LMNAPRMT5ENPP1 | |
| SCHEMBL28917146 | 0.87 | AR (0.77) | ARPARP1LMNAPRMT5ENPP1 | |
| SCHEMBL12955526 | 0.87 | AR (0.77) | ARPARP1LMNAPRMT5ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515939-A | Novel phthalazine derivatives having an inhibitory activity on ectonucleotide pyrophosphatase-phosphodiesterase and their use | 谛希诺生物科技有限公司 | 2022-12-23 | — | — | CN | claimed |
| WO-2012167144-A1 | NANOCOATINGS FOR BIOLOGICAL MATERIALS | PAXVAX, INC. (US) | 2012-12-06 | — | — | WO | claimed |
| EP-0488209-B1 | Process for producing benzylphthalazinone derivatives and salts thereof | EISAI KAGAKU KK (JP) | 1996-05-22 | — | — | EP | claimed |
| US-5216151-A | High yield antihistamines; dehydration | EISAI CHEMICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | claimed |
| EP-0488209-A1 | Process for producing benzylphthalazinone derivatives and salts thereof | EISAI CHEMICAL CO., LTD. (JP) | 1992-06-03 | — | — | EP | claimed |
| EP-0174464-B1 | SUBSTITUTED BENZYL PHTHALAZINONE DERIVATIVES | ASTA Pharma AG (DE) | 1990-01-03 | — | — | EP | claimed |
| US-4841047-A | ANTIALLERGENS | AASTA PHARMA AG (DE) | 1989-06-20 | — | — | US | claimed |
| US-4704387-A | N-benzyl, phenethyl, methoxyethyl or allyl substituted benzylphthalazinones having antiallergic and antihistamine action | ASTA-WERKE AKTIENGESELLSCHAFT, CHEMISCHE FABRIK (DE) | 1987-11-03 | — | — | US | claimed |
| CN-86107627-A | The preparation method of novel 4-benzyl-1-(2H)-phthalazinone derivatives | — | 1987-07-15 | — | — | CN | claimed |
| US-4207112-A | STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1980-06-10 | — | — | US | claimed |
| CN-115515939-B | Novel phthalazine derivatives having activity of inhibiting exonucleotide pyrophosphatase-phosphodiesterase and their use | 谛希诺生物科技有限公司 | 2024-12-13 | — | — | CN | disclosed |
| EP-3475272-B1 | PHTHALAZINE DERIVATIVES AS INHIBITORS OF PARP1, PARP2 AND/OR TUBULIN USEFUL FOR THE TREATMENT OF CANCER | UNIV CALIFORNIA (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |
| US-20230159469-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF | TXINNO BIOSCIENCE INC. (KR) | 2023-05-25 | — | — | US | disclosed |
| US-20230159469-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF | TXINNO BIOSCIENCE INC. (KR) | 2023-05-25 | — | — | US | disclosed |
| US-4237215-A | DECOMPOSING N-HALO COMPOUND IN PRESENCE OF ORGANIC SILVER SALT TO PRODUCE SILVER HALIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-02 | — | — | US | disclosed |
| US-4207112-A | STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1980-06-10 | — | — | US | disclosed |
| US-4144072-A | CONTAINING A PHTHALAZINONE AND A PHTHALIMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1979-03-13 | — | — | US | disclosed |
| US-4125403-A | ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, PHTHALAZINONE, AND A BENZOXAZINEDIONE OR QUINAZOLINEDIONE | FUJI PHOTO FILM CO., LTD. | 1978-11-14 | — | — | US | disclosed |
| US-4076534-A | Heat developable light-sensitive material | FUJI PHOTO FILM CO., LTD. (JA) | 1978-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159469-A1 | NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOF | ENPP1, ENPP3, PPA1 | AR 4407/4885PARP1 2763/4885LMNA 4507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.