Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333379 | 0.79 | NPC1 (0.41) | SMN1; SMN2NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL29411166 | 0.79 | NPC1 (0.41) | SMN1; SMN2NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL2565267 | 0.76 | NPC1 (0.40) | SMN1; SMN2NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL2565240 | 0.75 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL6449905 | 0.73 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL4639985 | 0.72 | NPC1 (0.40) | SMN1; SMN2NPC1RAB9AMAPTCYP1A2 | |
| Benzene SCHEMBL28160719 | 0.71 | NPC1 (0.49) | SMN1; SMN2NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL11473722 | 0.71 | CLCN2 (0.41) | SMN1; SMN2MAPTALDH1A1KMT2AHPGD | |
| SCHEMBL586754 | 0.71 | NPC1 (0.49) | SMN1; SMN2NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL25093172 | 0.69 | GABRA1 (0.39) | MAPTCYP1A2ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890999-B1 | CYCLOAKYLIDENE- (ORTHO SUBSTITUTED PHENYL) -ACETONITRILES AND THEIR USE AS ODORANTS | GIVAUDAN SA (CH) | 2011-11-02 | — | — | EP | claimed |
| US-7655701-B2 | Cycloalkylidene-(ortho substituted phenyl)-acetonitriles and their use as odorants | GIVAUDAN SA (CH) | 2010-02-02 | — | — | US | claimed |
| US-20080200554-A1 | Cycloaklyldiene-(Ortho Substituted Phenyl)-Acetonitriles and Their Use as Odorants | GIVAUDAN SA (CH) | 2008-08-21 | — | — | US | claimed |
| CN-101198585-A | Cycloakylidene- (ortho substituted phenyl) -acetonitriles and their use as odorants | GIVAUDAN SA (CH) | 2008-06-11 | — | — | CN | claimed |
| EP-1890999-A1 | CYCLOAKYLIDENE- (ORTHO SUBSTITUTED PHENYL) -ACETONITRILES AND THEIR USE AS ODORANTS | Givaudan SA (CH) | 2008-02-27 | — | — | EP | claimed |
| WO-2006133592-A1 | CYCLOAKYLIDENE- (ORTHO SUBSTITUTED PHENYL) -ACETONITRILES AND THEIR USE AS ODORANTS | GIVAUDAN SA (CH) | 2006-12-21 | — | — | WO | claimed |
| CN-101198585-B | Cycloakylidene- (ortho substituted phenyl) -acetonitriles and their use as odorants | GIVAUDAN S.A. (CH) | 2011-12-07 | — | — | CN | disclosed |
| EP-1890999-B1 | CYCLOAKYLIDENE- (ORTHO SUBSTITUTED PHENYL) -ACETONITRILES AND THEIR USE AS ODORANTS | GIVAUDAN SA (CH) | 2011-11-02 | — | — | EP | disclosed |
| US-7655701-B2 | Cycloalkylidene-(ortho substituted phenyl)-acetonitriles and their use as odorants | GIVAUDAN SA (CH) | 2010-02-02 | — | — | US | disclosed |
| US-20080200554-A1 | Cycloaklyldiene-(Ortho Substituted Phenyl)-Acetonitriles and Their Use as Odorants | GIVAUDAN SA (CH) | 2008-08-21 | — | — | US | disclosed |
| CN-101198585-A | Cycloakylidene- (ortho substituted phenyl) -acetonitriles and their use as odorants | GIVAUDAN SA (CH) | 2008-06-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200554-A1 | Cycloaklyldiene-(Ortho Substituted Phenyl)-Acetonitriles and Their Use as Odorants | OR10J3, OR51E2, OPRD1 | SMN1; SMN2 3788/4885NPC1 2179/4885RAB9A 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.