Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25469785 | 0.77 | EIF4A3 (0.32) | CAMKK2 | |
| SCHEMBL25624159 | 0.77 | LRRK2 (0.30) | — | |
| SCHEMBL24005905 | 0.72 | PIM1 (0.34) | — | |
| SCHEMBL26137564 | 0.71 | CXCR2 (0.32) | — | |
| SCHEMBL24005328 | 0.66 | — | — | |
| SCHEMBL25626710 | 0.65 | — | — | |
| SCHEMBL24006081 | 0.64 | TRPA1 (0.31) | — | |
| SCHEMBL19105605 | 0.64 | MAP3K12 (0.41) | CAMKK2 | |
| SCHEMBL15417374 | 0.63 | JAK2 (0.36) | KDM5A | |
| SCHEMBL29643881 | 0.62 | AXL (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | BCL2, BCL2L2, BCL2L1 | CAMKK2 381/4885KDM5A 3472/4885TYK2 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.