Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
| ▸ | ELOC | Q15369 | 1/20 | 0.35 |
| ▸ | ELOB | Q15370 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25954752 | 1.00 | ELANE (0.38) | ELANECA1CA2CA7PREP | |
| SCHEMBL18212482 | 0.86 | KMT2A (0.40) | ELANECA1CA2CA7PREP | |
| SCHEMBL24698048 | 0.85 | ELANE (0.49) | ELANECA1CA2CA7PREP | |
| SCHEMBL14751030 | 0.83 | CA1 (0.39) | ELANECA1CA2CA7PREP | |
| SCHEMBL30237869 | 0.82 | VHL (0.36) | ELANECTSLCTSBCTSKVHL | |
| SCHEMBL25650708 | 0.82 | VHL (0.36) | ELANECTSLCTSBCTSKVHL | |
| SCHEMBL25650779 | 0.81 | ALDH1A1 (0.35) | CTSKTSHR | |
| SCHEMBL25651059 | 0.80 | CCR1 (0.32) | ELANECTSLCTSBCTSK | |
| SCHEMBL24697478 | 0.80 | CTSV (0.35) | ELANECTSLCTSBCTSK | |
| SCHEMBL14737063 | 0.80 | JAK2 (0.45) | ELANECA1CA2CA7PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114516-A2 | CELL-PERMEANT INHIBITORS OF VIRAL CYSTEINE PROTEASES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-06-22 | — | — | WO | disclosed |