SCHEMBL2565488

SCHEMBL2565488

CC1(C(c2ccc(O)cc2)c2ccc(O)cc2)C=CC=CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.36
ESR2 Q92731 6/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
CYP2C9 P11712 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
PGR P06401 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
AR P10275 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CHRM1 P11229 1/20 0.33
ALOX15 P16050 1/20 0.33
DRD1 P21728 1/20 0.33
TBXA2R P21731 1/20 0.33
PTGS1 P23219 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1002008 1.00 ESR1 (0.36) ESR1ESR2PDCD1CD274CYP2C9
SCHEMBL472087 0.85 ESR1 (0.31) ESR1ESR2ALDH1A1KDM4E
SCHEMBL472176 0.85 ESR1 (0.31) ESR1ESR2ALDH1A1KDM4E
SCHEMBL4432626 0.85 ESR1 (0.39) ESR1ESR2PDCD1CD274CYP2C9
SCHEMBL8767421 0.79
SCHEMBL20473388 0.76 ESR1 (0.40) ESR1ESR2PDCD1CD274CYP2C9
SCHEMBL20473389 0.76 ESR1 (0.40) ESR1ESR2PDCD1CD274CYP2C9
SCHEMBL14325806 0.75 ESR1 (0.35) ESR1ESR2PDCD1CD274CYP2C9
SCHEMBL30206999 0.72 ESR1 (0.42) ESR1ESR2PDCD1CD274CYP2C9
SCHEMBL5670868 0.70 ESR1 (0.40) ESR1ESR2PDCD1CD274CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993791-B2 Process for producing epoxy compounds SHOWA DENKO K.K. (JP) 2015-03-31 US disclosed
EP-2383264-B1 EPOXY COMPOUND PRODUCTION METHOD SHOWA DENKO KK (JP) 2015-03-04 EP disclosed
US-20120302775-A1 PROCESS FOR PRODUCING EPOXY COMPOUNDS SHOWA DENKO K.K. (JP) 2012-11-29 US disclosed
EP-2518061-A1 PROCESS FOR PRODUCTION OF EPOXY COMPOUND Showa Denko K.K. (JP) 2012-10-31 EP disclosed
EP-2383264-A1 EPOXY COMPOUND PRODUCTION METHOD Showa Denko K.K. (JP) 2011-11-02 EP disclosed
US-4180405-A COLOR-FORMING LACTONES OR SPIROPYRANS WITH CYCLIC POLYKETO COLOR PRECURSOR GRAPHIC CONTROLS CORPORATION (US) 1979-12-25 US disclosed
US-4097288-A Heat sensitive recording composition containing a complexed phenolics and a spiropyran or leuco lactone GRAPHIC CONTROLS CORPORATION 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120302775-A1 PROCESS FOR PRODUCING EPOXY COMPOUNDS AOX1, EPX, CYP2E1 ESR1 159/4885ESR2 150/4885PDCD1 3683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.