Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NMT2 | O60551 | 1/20 | 0.45 |
| ▸ | NMT1 | P30419 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29055040 | 0.89 | PDGFRB (0.58) | MEN1KMT2APDE4BMAPK10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL23726881 | 0.88 | PDGFRB (0.57) | MEN1KMT2APDE4BMAPK10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30080064 | 0.88 | PDGFRB (0.57) | MEN1KMT2APDE4BMAPK10ALDH1A1 | |
| SCHEMBL25656125 | 0.81 | MEN1 (0.57) | MEN1KMT2APDE4BMAPK10ALDH1A1 | |
| SCHEMBL25656123 | 0.79 | MEN1 (0.55) | MEN1KMT2APDE4BMAPK10ALDH1A1 | |
| SCHEMBL25656121 | 0.76 | MEN1 (0.49) | MEN1KMT2APDE4BMAPK10ALDH1A1 | |
| SCHEMBL13262173 | 0.74 | PDE4B (0.51) | MEN1KMT2APDE4BMAPK10ALDH1A1 | |
| SCHEMBL25656103 | 0.73 | LRRK2 (0.48) | — | |
| SCHEMBL19021357 | 0.71 | KMT2A (0.49) | MEN1KMT2APDE4BMAPK10ALDH1A1 | |
| SCHEMBL2914728 | 0.71 | PDGFRB (0.70) | MEN1KMT2AMAPK10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183212-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | STINGRAY THERAPEUTICS INC (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183212-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | ENPP1, ENPP3, PPA1 | MEN1 796/4885KMT2A 4288/4885PDE4B 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.