Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PPM1B | O75688 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27534001 | 0.98 | SOAT1 (0.58) | SOAT1ALDH1A1MAPTGAAPPM1B | |
| SCHEMBL6153652 | 0.94 | SOAT1 (0.54) | SOAT1ALDH1A1MAPTGAAPPM1B | |
| SCHEMBL27549861 | 0.92 | ALDH1A1 (0.54) | SOAT1ALDH1A1MAPTGAAMEN1 | |
| Hydrochloric Acid SCHEMBL28100636 | 0.92 | SOAT1 (0.52) | SOAT1ALDH1A1MAPTGAAPPM1B | |
| Hydrochloric Acid SCHEMBL27578586 | 0.90 | ALDH1A1 (0.53) | SOAT1ALDH1A1MAPTGAAMEN1 | |
| Hydrochloric Acid SCHEMBL28866440 | 0.87 | SOAT1 (0.47) | SOAT1ALDH1A1MAPTGAAPPM1B | |
| SCHEMBL17716490 | 0.87 | SOAT1 (0.47) | SOAT1ALDH1A1MAPTGAAPPM1B | |
| SCHEMBL26620877 | 0.87 | SOAT1 (0.47) | SOAT1ALDH1A1MAPTGAAPPM1B | |
| SCHEMBL2375356 | 0.83 | MAPT (0.60) | SOAT1ALDH1A1MAPTPPM1BPTPN1 | |
| SCHEMBL8891623 | 0.83 | MAPT (0.60) | SOAT1ALDH1A1MAPTPPM1BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119613408-A | Bicyclic ketone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-110914271-B | Bicyclic ketone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-111050765-B | Spiro compounds and methods of making and using the same | H.隆德贝克有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-112390749-A | Synthesis method of cabozantinib and intermediate thereof | 鲁南制药集团股份有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-111050765-A | Spiro compounds and methods of making and using the same | 隆德贝克拉荷亚研究中心有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-110914271-A | Bicyclic ketone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2020-03-24 | — | — | CN | disclosed |
| EP-3164388-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS RETINOID-RELATED ORPHAN RECEPTOR (ROR) GAMMA-T INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2017-05-10 | — | — | EP | disclosed |
| CN-106107406-A | Improve the method for the stability of sweetness enhancers and comprise the compositions of stable sweetness enhancers | 赛诺米克斯公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-103153096-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 赛诺米克斯公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-103153096-A | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | SENOMYX INC | 2013-06-12 | — | — | CN | disclosed |
| WO-2010132760-A9 | ANTIBACTERIAL DERIVATIVES OF TOBRAMYCIN | ACHAOGEN, INC. (US) | 2011-11-03 | — | — | WO | disclosed |
| WO-2010132765-A9 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2011-10-13 | — | — | WO | disclosed |
| CN-102212062-A | Derivative of amino ester, salt thereof and using method | DONGGUAN CHANGAN EAST SUNSHINE DRUG R & D CO LTD | 2011-10-12 | — | — | CN | disclosed |
| CN-102086211-A | Aromatic heterocyclic compounds serving as protein kinase inhibitor | SHENZHEN HEC INDUSTRY DEV CO LTD | 2011-06-08 | — | — | CN | disclosed |
| CN-1921867-B | Nucleoside phosphonate derivatives for the treatment of HIV infection | LG LIFE SCIENCES LTD | 2010-05-05 | — | — | CN | disclosed |
| CN-100347185-C | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCE CO LTD (KR) | 2007-11-07 | — | — | CN | disclosed |
| CN-1921867-A | Nucleoside phosphonate derivatives for the treatment of HIV infection | LG LIFE SCIENCES LTD (KR) | 2007-02-28 | — | — | CN | disclosed |
| CN-1744899-A | Piperidine derivatives as CCR5 antagonists | SMITHKLINE BEECHAM CORP (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1487949-A | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | ��ʽ����LG������ѧ | 2004-04-07 | — | — | CN | disclosed |