Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PPM1B | O75688 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27549861 | 0.94 | ALDH1A1 (0.54) | SOAT1ALDH1A1MAPTSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL28100636 | 0.94 | SOAT1 (0.52) | SOAT1ALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL2565618 | 0.94 | SOAT1 (0.61) | SOAT1ALDH1A1MAPTGAAKMT2A | |
| Hydrochloric Acid SCHEMBL27578586 | 0.92 | ALDH1A1 (0.53) | SOAT1ALDH1A1MAPTSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL27534001 | 0.92 | SOAT1 (0.58) | SOAT1ALDH1A1MAPTGAAPPM1B | |
| SCHEMBL29427 | 0.83 | — | — | |
| SCHEMBL17716490 | 0.82 | SOAT1 (0.47) | SOAT1ALDH1A1MAPTGAAKMT2A | |
| Hydrochloric Acid SCHEMBL28866440 | 0.82 | SOAT1 (0.47) | SOAT1ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL26620877 | 0.82 | SOAT1 (0.47) | SOAT1ALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL28874519 | 0.81 | SLC6A1 (0.47) | SOAT1ALDH1A1MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117398474-A | Bioactive conjugate, preparation method and application thereof | 苏州宜联生物医药有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-116354923-A | Nitrogen-containing heterocyclic compound and application thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-116249556-A | Antibody conjugation chemical inducer for degrading BRM and method thereof | 基因泰克公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-114901658-A | Nitrogen-containing heterocyclic ring autotaxin inhibitor, and composition and application thereof | 四川海思科制药有限公司 | 2022-08-12 | — | — | CN | disclosed |
| EP-3157938-B1 | HETERO FUNCTIONAL BINDING SYSTEMS | ANTEO TECH PTY LTD (AU) | 2022-03-16 | — | — | EP | disclosed |
| CN-113874374-A | Hydrogenated pyridopyrimidine derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-12-31 | — | — | CN | disclosed |
| US-10768176-B2 | Hetero functional binding systems | ANTEO TECHNOLOGIES PTY LTD (AU) | 2020-09-08 | — | — | US | disclosed |
| US-20170115285-A1 | HETERO FUNCTIONAL BINDING SYSTEMS | ANTEO TECHNOLOGIES PTY LTD (AU) | 2017-04-27 | — | — | US | disclosed |
| EP-3157938-A1 | HETERO FUNCTIONAL BINDING SYSTEMS | Anteo Technologies Pty Ltd. (AU) | 2017-04-26 | — | — | EP | disclosed |
| WO-2015192183-A1 | HETERO FUNCTIONAL BINDING SYSTEMS | ANTEO TECHNOLOGIES PTY LTD (AU) | 2015-12-23 | — | — | WO | disclosed |
| EP-1569646-A2 | PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004054974-A2 | PIPERIDINE DERIVATIVES AS CCR5 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-07-01 | — | — | WO | disclosed |