SCHEMBL25657283

SCHEMBL25657283

CC(C)Cc1ccc2c(-c3c(-c4ccccc4)c(C(F)(F)F)nn3C3CCCCO3)ncnc2c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
EGFR P00533 1/20 0.31
BTK Q06187 1/20 0.31
ATR Q13535 3/20 0.31
CMKLR1 Q99788 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
TSHR P16473 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
ATM Q13315 1/20 0.30
HSD17B10 Q99714 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
AAK1 Q2M2I8 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
RXRA P19793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25657279 0.76 CFTR (0.34) ATRALDH1A1L3MBTL1RXRARXRB
SCHEMBL22915716 0.71 MEN1 (0.36) KDM4EAAK1RAB9ASMN1; SMN2
SCHEMBL25657280 0.70 POLB (0.37) ATRKDM4EALDH1A1HSD17B10L3MBTL1
SCHEMBL25657281 0.70 CYP4F2 (0.36) ATRKDM4EALDH1A1TSHRHSD17B10
SCHEMBL13183780 0.68 RXRA (0.37) ALDH1A1GAAHSD17B10L3MBTL1SMN1; SMN2
SCHEMBL31469324 0.68 ATR (0.40) PDCD1CD274ATRNPC1RAB9A
SCHEMBL1981621 0.67 DRD1 (0.34) KDM4EALDH1A1HSD17B10L3MBTL1RXRA
SCHEMBL26114155 0.66 AURKB (0.40) DRD1
SCHEMBL1979590 0.65 DRD1 (0.35) ALDH1A1SMN1; SMN2RXRARXRBRXRG
SCHEMBL25657282 0.65 POLB (0.36) ATRKDM4EALDH1A1HSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11678566-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11678566-B2 Organometallic compound and organic light-emitting device including the same L1CAM, AP1M1, PYM1 PDCD1 902/4885CD274 121/4885EGFR 3948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.