SCHEMBL25657282

SCHEMBL25657282

CC1(C)OB(c2c(-c3ccccc3)c(C(F)(F)F)nn2C2CCCCO2)OC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.36
KDM4E B2RXH2 1/20 0.33
DRD1 P21728 1/20 0.33
LPL P06858 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HPGD P15428 1/20 0.31
LMNA P02545 2/20 0.30
GLA P06280 1/20 0.30
ATR Q13535 1/20 0.30
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14800595 0.76 IDO1 (0.34)
SCHEMBL26110492 0.73 GAA (0.36) KDM4EDRD1LPLLIPGHSD17B10
SCHEMBL3628093 0.72 MPO (0.36) POLBKDM4EHSD17B10MEN1ALDH1A1
SCHEMBL10327099 0.71 ATR (0.33) ATR
SCHEMBL177354 0.71 CYP11B2 (0.37) ALDH1A1ATR
SCHEMBL25657280 0.71 POLB (0.37) POLBKDM4EDRD1HSD17B10MEN1
SCHEMBL25657281 0.70 CYP4F2 (0.36) POLBKDM4EDRD1HSD17B10MEN1
SCHEMBL26110405 0.70 LPL (0.35) LPLLIPGALDH1A1LMNAATR
SCHEMBL17251576 0.69 GAA (0.33)
SCHEMBL29363943 0.69 DGAT2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11678566-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11678566-B2 Organometallic compound and organic light-emitting device including the same L1CAM, AP1M1, PYM1 POLB 2260/4885KDM4E 2411/4885DRD1 445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.