SCHEMBL2565824

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2570776	0.91	GRK2 (0.55)	GRK2ROCK1GRK5RPS6KB1RPS6KA1
	SCHEMBL2567800	0.90	GRK2 (0.54)	GRK2ROCK1GRK5RPS6KB1RPS6KA1
	SCHEMBL2569277	0.86	GRK2 (0.68)	GRK2ROCK1GRK5RPS6KB1RPS6KA1
	SCHEMBL3885974	0.85	ROCK1 (0.71)	GRK2ROCK1GRK5RPS6KB1RPS6KA1
	SCHEMBL2569452	0.83	PKM (0.52)	GRK2ROCK1GRK5RPS6KB1RPS6KA1
	SCHEMBL2567097	0.83	GRK2 (0.77)	GRK2ROCK1GRK5RPS6KB1RPS6KA1
	SCHEMBL2569454	0.78	GRK2 (0.44)	GRK2ROCK1GRK5RPS6KB1RPS6KA1
	SCHEMBL13789092	0.78	TSHR (0.54)	GRK2ROCK1GRK5RPS6KB1RPS6KA1
	SCHEMBL2569300	0.77	ROCK1 (0.42)	GRK2ROCK1GRK5RPS6KB1RPS6KA1
	SCHEMBL2568042	0.76	GRK2 (0.69)	GRK2ROCK1GRK5RPS6KB1RPS6KA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.