SCHEMBL25658474

SCHEMBL25658474

N#Cc1cc(F)c(-c2ccc(C(F)(F)F)cc2C#N)cc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.50
FEN1 P39748 1/20 0.50
TRPV4 Q9HBA0 2/20 0.44
CYP11B1 P15538 3/20 0.41
CYP11B2 P19099 3/20 0.41
AR P10275 2/20 0.37
MPL P40238 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.36
KIF11 P52732 1/20 0.36
PTPN1 P18031 1/20 0.35
PTPN6 P29350 1/20 0.35
PTPN11 Q06124 1/20 0.35
TAS2R14 Q9NYV8 1/20 0.35
XDH P47989 1/20 0.34
GABRA1 P14867 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
GABRA2 P47869 2/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25658482 0.90 ALOX5AP (0.49) ALOX5APFEN1TRPV4CYP11B1CYP11B2
SCHEMBL20111586 0.88 AR (0.45) ALOX5APFEN1TRPV4CYP11B1CYP11B2
SCHEMBL283060 0.81 TRPV4 (0.45) ALOX5APFEN1TRPV4CYP11B1CYP11B2
SCHEMBL20111535 0.79 AR (0.46) ALOX5APFEN1CYP11B1CYP11B2AR
SCHEMBL20444106 0.78 TRPV4 (0.60) TRPV4CYP11B1CYP11B2
SCHEMBL25658520 0.78 ALOX5AP (0.45) ALOX5APFEN1CYP11B1CYP11B2AR
SCHEMBL495426 0.77 CYP11B1 (0.57) ALOX5APFEN1TRPV4CYP11B1CYP11B2
SCHEMBL19903442 0.77 TRPV4 (0.47) ALOX5APFEN1TRPV4CYP11B1CYP11B2
SCHEMBL25658455 0.76 ALOX5AP (0.46) ALOX5APFEN1CYP11B1CYP11B2AR
SCHEMBL25658426 0.76 ALOX5AP (0.55) ALOX5APFEN1TRPV4CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11825743-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
US-11825743-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
EP-3585777-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11825743-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OCIAD2 ALOX5AP 3126/4885FEN1 1566/4885TRPV4 243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.