SCHEMBL20111535

SCHEMBL20111535

N#Cc1cc(F)c(F)cc1-c1ccc(C(F)(F)F)cc1C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AR P10275 13/20 0.46
ALOX5AP P20292 2/20 0.43
FEN1 P39748 2/20 0.43
TRPA1 O75762 1/20 0.39
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.37
PGR P06401 1/20 0.37
CES2 O00748 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20111586 0.89 AR (0.45) ARALOX5APFEN1CYP11B1CYP11B2
SCHEMBL25658482 0.89 ALOX5AP (0.49) ARALOX5APFEN1CYP11B1CYP11B2
SCHEMBL25658407 0.84 KIF11 (0.46) ARTRPA1GLAPOLBGAA
SCHEMBL20616786 0.81 AR (0.58) ARTRPA1PGR
SCHEMBL25658474 0.79 ALOX5AP (0.50) ARALOX5APFEN1CYP11B1CYP11B2
SCHEMBL20111536 0.78 ALOX5AP (0.47) ARALOX5APFEN1CYP11B1CYP11B2
SCHEMBL28676412 0.77 TSHR (0.56) ARALOX5APFEN1GLAPOLB
SCHEMBL20111529 0.77 AR (0.39) ARALOX5APFEN1GLAPOLB
SCHEMBL1996176 0.76 AR (0.53) ARCES2
SCHEMBL1996075 0.76 AR (0.73) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11825743-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
US-10971688-B2 Organic molecules for use in organic optoelectronic devices CYNORA GMBH (DE) 2021-04-06 US disclosed
US-20190248741-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-15 US disclosed
EP-3360945-B1 ORGANIC ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-04-24 EP disclosed
WO-2018077492-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11825743-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OCIAD2 AR 4630/4885ALOX5AP 3126/4885FEN1 1566/4885
US-10971688-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OPRM1 AR 4611/4885ALOX5AP 2592/4885FEN1 1121/4885
US-20190248741-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 AR 4386/4885ALOX5AP 3253/4885FEN1 1286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.