SCHEMBL25659643

SCHEMBL25659643

N#Cc1ccc2c(c1)c1ccccc1n2-c1cc(-c2ccc(C(F)(F)F)cc2C#N)c(-n2c3ccccc3c3cc(C#N)ccc32)cc1C#N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.37
ALOX5AP P20292 1/20 0.34
FEN1 P39748 1/20 0.34
SCN9A Q15858 1/20 0.33
RORC P51449 4/20 0.32
ENPP3 O14638 1/20 0.32
PDK2 Q15119 1/20 0.32
CNR2 P34972 1/20 0.32
MAT2A P31153 1/20 0.32
PTPN1 P18031 1/20 0.31
PTPN6 P29350 1/20 0.31
PTPN11 Q06124 1/20 0.31
DGAT1 O75907 1/20 0.31
SOAT1 P35610 1/20 0.31
KCNH2 Q12809 1/20 0.31
HSP90AA1 P07900 1/20 0.31
PSEN1 P49768 1/20 0.31
PSEN2 P49810 1/20 0.31
APH1B Q8WW43 1/20 0.31
NCSTN Q92542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26777703 0.96 KIF11 (0.37) KIF11ALOX5APFEN1SCN9ARORC
SCHEMBL25659648 0.96 ALOX5AP (0.36) KIF11ALOX5APFEN1SCN9AMAT2A
SCHEMBL25659647 0.95 KIF11 (0.39) KIF11ALOX5APFEN1SCN9APDK2
SCHEMBL25659650 0.93 KIF11 (0.40) KIF11ALOX5APFEN1SCN9ARORC
SCHEMBL25659738 0.93 ALOX5AP (0.40) KIF11ALOX5APFEN1MAT2ADGAT1
SCHEMBL20111849 0.92 KIF11 (0.36) KIF11SCN9ARORC
SCHEMBL25659649 0.90 KIF11 (0.45) KIF11ALOX5APFEN1SCN9ACNR2
SCHEMBL25659646 0.90 ALOX5AP (0.36) KIF11ALOX5APFEN1SCN9APTPN1
SCHEMBL25658583 0.89 KIF11 (0.36) KIF11SCN9ARORCHSP90AA1
SCHEMBL25659627 0.89 KIF11 (0.40) KIF11ALOX5APFEN1SCN9ARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11825743-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
EP-3585777-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11825743-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OCIAD2 KIF11 3288/4885ALOX5AP 3126/4885FEN1 1566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.