SCHEMBL25659646

SCHEMBL25659646

N#Cc1ccc2c3ccc(C#N)cc3n(-c3cc(-c4ccc(C(F)(F)F)cc4C#N)c(-n4c5cc(C#N)ccc5c5ccc(C#N)cc54)cc3C#N)c2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.36
FEN1 P39748 1/20 0.36
SCN9A Q15858 1/20 0.35
KIF11 P52732 2/20 0.35
PTPN1 P18031 1/20 0.33
PTPN6 P29350 1/20 0.33
PTPN11 Q06124 1/20 0.33
DGAT1 O75907 1/20 0.33
SOAT1 P35610 1/20 0.33
KCNH2 Q12809 1/20 0.33
PSEN1 P49768 1/20 0.32
PSEN2 P49810 1/20 0.32
APH1B Q8WW43 1/20 0.32
NCSTN Q92542 1/20 0.32
APH1A Q96BI3 1/20 0.32
PSENEN Q9NZ42 1/20 0.32
DDR1 Q08345 1/20 0.32
PTGDR2 Q9Y5Y4 3/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25659647 0.96 KIF11 (0.39) ALOX5APFEN1SCN9AKIF11PTPN1
SCHEMBL25659651 0.93 KIF11 (0.40) ALOX5APFEN1SCN9AKIF11PTPN1
SCHEMBL25659740 0.92 ALOX5AP (0.41) ALOX5APFEN1SCN9AKIF11PTPN1
SCHEMBL25659648 0.92 ALOX5AP (0.36) ALOX5APFEN1SCN9AKIF11PTPN1
SCHEMBL25659735 0.91 KIF11 (0.44) ALOX5APFEN1SCN9AKIF11DGAT1
SCHEMBL20111856 0.91 AR (0.35) KIF11DGAT1SOAT1KCNH2PSEN1
SCHEMBL25659643 0.90 KIF11 (0.37) ALOX5APFEN1SCN9AKIF11PTPN1
SCHEMBL25658581 0.89 KIF11 (0.35) ALOX5APFEN1KIF11DGAT1SOAT1
SCHEMBL25659649 0.88 KIF11 (0.45) ALOX5APFEN1SCN9AKIF11TSHR
SCHEMBL26777239 0.88 KIF11 (0.39) ALOX5APFEN1SCN9AKIF11PSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11825743-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
EP-3585777-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11825743-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OCIAD2 ALOX5AP 3126/4885FEN1 1566/4885SCN9A 1552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.