Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24863354 | 0.94 | CA12 (0.36) | ELANENPC1LMNAKLKB1MAPT | |
| SCHEMBL24863355 | 0.93 | LMNA (0.38) | ELANENPC1LMNAKLKB1MAPT | |
| SCHEMBL25659769 | 0.87 | KLKB1 (0.46) | KLKB1 | |
| SCHEMBL24863528 | 0.84 | KLKB1 (0.38) | NPC1LMNAKLKB1RAB9AGRM2 | |
| SCHEMBL25659772 | 0.81 | KLKB1 (0.32) | ELANEKLKB1MAPTGRM2 | |
| SCHEMBL25659962 | 0.81 | KLKB1 (0.32) | ELANEKLKB1MAPT | |
| SCHEMBL24863520 | 0.77 | KLKB1 (0.52) | KLKB1 | |
| SCHEMBL25659886 | 0.76 | KLKB1 (0.38) | LMNAKLKB1MAPTKDM4EALDH1A1 | |
| SCHEMBL24863505 | 0.76 | KLKB1 (0.43) | NPC1LMNAKLKB1MAPTKDM4E | |
| SCHEMBL21354835 | 0.76 | KLKB1 (0.49) | KLKB1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167098-A1 | HETEROCYCLIC COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167098-A1 | HETEROCYCLIC COMPOUND | CYP11B2, CYP4F11, CYP11B1 | ELANE 2441/4885NPC1 95/4885LMNA 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.