SCHEMBL25660307

SCHEMBL25660307

c1ccc(-c2ccc3c4cc5c(cc4n(-c4ccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)cc4)c3c2)sc2ccccc25)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HSP90AA1 P07900 1/20 0.33
AVPR1A P37288 1/20 0.33
ATM Q13315 2/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GPR3 P46089 1/20 0.33
LIMK1 P53667 1/20 0.32
RXRA P19793 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIK3CA P42336 1/20 0.32
PI4KA P42356 1/20 0.32
PI4KB Q9UBF8 1/20 0.32
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25133076 0.94 ATM (0.40) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL18505399 0.94 ATM (0.40) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL20129518 0.93 PIM3 (0.34) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL10014532 0.93 ATM (0.41) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL25660305 0.92 KDM4E (0.36) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL24216722 0.92 KDM4E (0.36) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL25660306 0.92 ALDH1A1 (0.33) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL24013540 0.92 ATM (0.38) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL21128190 0.92 ALDH1A1 (0.35) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL21472388 0.92 PIM3 (0.37) MAPTALDH1A1HPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230276690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-31 US disclosed
US-20230276690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-08-31 US disclosed
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-05-18 US disclosed
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276690-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, TELO2, LIMS1 MAPT 2197/4885ALDH1A1 149/4885HPGD 3119/4885
US-20230157156-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, VDAC2, ICOSLG MAPT 1032/4885ALDH1A1 604/4885HPGD 3854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.