Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25522013 | 0.93 | PKM (0.42) | SMN1; SMN2GAAPDK2PDK1KMT2A | |
| SCHEMBL17454459 | 0.90 | PIK3CD (0.38) | SMN1; SMN2GAAKMT2ABRD4 | |
| SCHEMBL17437926 | 0.83 | HCAR3 (0.41) | SMN1; SMN2GAAPDK2PDK1KMT2A | |
| SCHEMBL4043341 | 0.83 | KMT2A (0.43) | SMN1; SMN2GAAPDK2PDK1KMT2A | |
| SCHEMBL23135531 | 0.81 | BRD4 (0.40) | SMN1; SMN2GAAPDK2PDK1KMT2A | |
| SCHEMBL17437902 | 0.81 | F2 (0.46) | SMN1; SMN2GAAPDK2PDK1KMT2A | |
| SCHEMBL25854000 | 0.81 | PDK2 (0.43) | SMN1; SMN2GAAPDK2PDK1KMT2A | |
| SCHEMBL23069041 | 0.77 | NR3C2 (0.41) | SMN1; SMN2GAAPDK2PDK1KMT2A | |
| SCHEMBL23367056 | 0.77 | KMT2A (0.39) | SMN1; SMN2GAAPDK2PDK1KMT2A | |
| SCHEMBL23135526 | 0.77 | BRD4 (0.43) | SMN1; SMN2KMT2APKMMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227437-A1 | IMMUNOMODULATOR | HITGEN INC (CN) | 2023-07-20 | — | — | US | disclosed |
| EP-4177249-A1 | IMMUNOMODULATOR | Hitgen Inc. (CN) | 2023-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227437-A1 | IMMUNOMODULATOR | IL17A, IL2, IL2RA | SMN1; SMN2 4839/4885GAA 2382/4885PDK2 2452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.