SCHEMBL25660676

SCHEMBL25660676

N[C@]1(C(=O)O)CC1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.65
GRM6 O15303 9/20 0.52
GRM4 Q14833 7/20 0.52
CYP1A2 P05177 3/20 0.52
CYP2C19 P33261 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
ALOX15 P16050 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
GRM8 O00222 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
KDM4E B2RXH2 1/20 0.52
GRM2 Q14416 13/20 0.50
GRM3 Q14832 8/20 0.50
GRM5 P41594 5/20 0.47
GRM1 Q13255 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5479431 1.00 SLC6A4 (0.65) SLC6A4GRM6GRM4CYP1A2CYP2C19
SCHEMBL9665784 0.80 SLC6A4 (0.50) SLC6A4GRM6GRM4CYP1A2CYP2C19
SCHEMBL14158525 0.80 SLC6A4 (1.00) SLC6A4GRM6GRM4CYP1A2CYP2C19
SCHEMBL179722 0.80 SLC6A4 (1.00) SLC6A4GRM6GRM4CYP1A2CYP2C19
SCHEMBL2229860 0.80 SLC6A4 (1.00) SLC6A4GRM6GRM4CYP1A2CYP2C19
SCHEMBL14158524 0.80 SLC6A4 (1.00) SLC6A4GRM6GRM4CYP1A2CYP2C19
SCHEMBL15909554 0.76
SCHEMBL15428478 0.76
Hydrochloric Acid SCHEMBL25384535 0.74
Hydrochloric Acid SCHEMBL9277699 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF PAICS, LNPEP, DNPEP SLC6A4 3739/4885GRM6 2966/4885GRM4 3291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.