Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 10/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 8/20 | 0.47 |
| ▸ | GRM6 | O15303 | 6/20 | 0.47 |
| ▸ | GRM5 | P41594 | 6/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 5/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GRM8 | O00222 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14158524 | 1.00 | SLC6A4 (1.00) | SLC6A4CYP1A2ALOX15ALDH1A1KDM4E | |
| SCHEMBL2229860 | 1.00 | SLC6A4 (1.00) | SLC6A4CYP1A2ALOX15ALDH1A1KDM4E | |
| SCHEMBL179722 | 1.00 | SLC6A4 (1.00) | SLC6A4CYP1A2ALOX15ALDH1A1KDM4E | |
| SCHEMBL25660676 | 0.80 | SLC6A4 (0.65) | SLC6A4CYP1A2ALOX15ALDH1A1KDM4E | |
| SCHEMBL5479431 | 0.80 | SLC6A4 (0.65) | SLC6A4CYP1A2ALOX15ALDH1A1KDM4E | |
| SCHEMBL4755338 | 0.74 | SLC6A4 (0.59) | SLC6A4CYP1A2ALOX15ALDH1A1KDM4E | |
| SCHEMBL9088184 | 0.71 | SLC6A4 (0.55) | SLC6A4CYP1A2ALOX15ALDH1A1KDM4E | |
| SCHEMBL15514216 | 0.71 | SLC6A4 (0.55) | SLC6A4CYP1A2ALOX15ALDH1A1KDM4E | |
| SCHEMBL1064244 | 0.70 | CYP1A2 (1.00) | SLC6A4CYP1A2ALOX15ALDH1A1KDM4E | |
| SCHEMBL1063416 | 0.70 | CYP1A2 (1.00) | SLC6A4CYP1A2ALOX15ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170599-A1 | NEUROGENESIS BY MUSCARINIC RECEPTOR MODULATION | BRAINCELLS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |