Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | WNT1 | P04628 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25664007 | 1.00 | KMT2A (0.48) | KMT2APIK3CDBCHEGSK3BDYRK1A | |
| SCHEMBL25664000 | 0.89 | PIK3CD (0.47) | KMT2APIK3CDKDM4EALDH1A1TDP1 | |
| SCHEMBL25663999 | 0.89 | PIK3CD (0.47) | KMT2APIK3CDKDM4EALDH1A1TDP1 | |
| SCHEMBL25664009 | 0.89 | PIK3CD (0.47) | KMT2APIK3CDKDM4EALDH1A1TDP1 | |
| SCHEMBL23557645 | 0.86 | KMT2A (0.51) | KMT2AALDH1A1POLB | |
| SCHEMBL21047360 | 0.86 | KMT2A (0.51) | KMT2AALDH1A1POLB | |
| SCHEMBL30006184 | 0.85 | KMT2A (0.64) | KMT2APIK3CDBCHEGSK3BDYRK1A | |
| SCHEMBL12000479 | 0.81 | PIK3CD (0.48) | KMT2APIK3CDKDM4EALDH1A1TDP1 | |
| SCHEMBL13149470 | 0.80 | BCHE (0.47) | BCHEKDM4EALDH1A1KDM2B | |
| SCHEMBL23374567 | 0.80 | BCHE (0.63) | BCHEKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143612-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143612-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | HAVCR2, HMBS, VHL | KMT2A 346/4885PIK3CD 2759/4885BCHE 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.