SCHEMBL25664271

SCHEMBL25664271

CC(C)c1ccc(C(=O)Nc2ccc(-c3ccc(N)cc3S(=O)(=O)O)c(S(=O)(=O)O)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.52
▸ KDM4E B2RXH2 1/20 0.52
▸ CASP6 P55212 1/20 0.48
▸ CTDSP1 Q9GZU7 1/20 0.48
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ POLB P06746 1/20 0.48
▸ PKM P14618 1/20 0.48
▸ APEX1 P27695 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ CA12 O43570 1/20 0.46
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ CA9 Q16790 1/20 0.46
▸ PRMT1 Q99873 2/20 0.45
▸ RAPGEF4 Q8WZA2 1/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.44
▸ MAPT P10636 4/20 0.43
▸ TP53 P04637 1/20 0.43
▸ EGFR P00533 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19491776 0.88 CASP6 (0.46) LMNAKDM4ECASP6CTDSP1MEN1
SCHEMBL16208330 0.87 MAPT (0.55) LMNAKDM4ECASP6CTDSP1MEN1
SCHEMBL25664203 0.85 CASP6 (0.46) LMNAKDM4ECASP6CTDSP1MEN1
SCHEMBL15698717 0.82 CASP6 (0.46) LMNAKDM4ECASP6CTDSP1MEN1
SCHEMBL15698720 0.81 CASP6 (0.46) LMNAKDM4ECASP6CTDSP1MEN1
SCHEMBL19750415 0.81 MEN1 (0.42) KDM4ECTDSP1MEN1KMT2APOLB
SCHEMBL394298 0.79 MEN1 (0.60) LMNAKDM4ECASP6CTDSP1MEN1
SCHEMBL10877294 0.77 MEN1 (0.58) LMNAKDM4ECASP6CTDSP1MEN1
SCHEMBL23073991 0.77 PTGS1 (0.53) LMNAKDM4EMEN1KMT2APOLB
SCHEMBL17804058 0.76 NPC1 (0.60) KDM4ECTDSP1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230145287-A1 LINEAR POLARIZERS AND METHODS OF FORMING A LINEAR POLARIZER LIGHT POLYMERS HOLDING (KY) 2023-05-11 — — US disclosed
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