SCHEMBL25664294

SCHEMBL25664294

CSCC[C@@H](NC(=O)[C@@H](C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1CCCN1C(=O)[C@@H](Cc1c[nH]cn1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@H](CCSC)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCCN)C(=O)NCC(=O)NCC(=O)NCC(=O)NC(CCCCNC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)N[C@H](CCCCNCCC(=O)OCc1ccccc1)C(N)=O

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 3/20 0.64
▸ CTSS P25774 3/20 0.64
▸ CTSK P43235 3/20 0.64
▸ CTSH P09668 1/20 0.63
▸ GLP1R P43220 4/20 0.62
▸ GCGR P47871 3/20 0.62
▸ C5AR1 P21730 2/20 0.62
▸ NMBR P28336 2/20 0.59
▸ GRPR P30550 2/20 0.59
▸ CXCL8 P10145 4/20 0.57
▸ MC4R P32245 1/20 0.56
▸ MC5R P33032 1/20 0.56
▸ MC3R P41968 1/20 0.56
▸ MC1R Q01726 1/20 0.56
▸ CXCR4 P61073 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25665234 0.94 CTSL (0.69) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL26426177 0.93 CTSL (0.64) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL25664282 0.93 CTSL (0.66) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL25664250 0.92 CTSL (0.65) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL25665363 0.91 CTSL (0.69) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL25664212 0.91 CTSL (0.68) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL26428433 0.90 CTSL (0.65) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL25664225 0.89 CTSL (0.67) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL26426063 0.89 CTSL (0.64) CTSLCTSSCTSKCTSHGLP1R
SCHEMBL30439204 0.88 C5AR1 (0.66) CTSLCTSSCTSKCTSHGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230173086-A1 PEPTIDE CONJUGATES AND THERAPEUTIC AGENTS HAVING IMPROVED PHARMACOLOGICAL AND PHARMACOKINETIC PROPERTIES EAGLE RESOLUTE INVESTMENT LLC 2023-06-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230173086-A1 PEPTIDE CONJUGATES AND THERAPEUTIC AGENTS HAVING IMPROVED PHARMACOLOGICAL AND PHARMACOKINETIC PROPERTIES VIP, DNPEP, CD74 CTSL 56/4885CTSS 369/4885CTSK 226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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