SCHEMBL26426063

CSCC[C@@H](NC(=O)[C@@H](C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H]1CCCN1C(=O)[C@@H](Cc1c[nH]cn1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@H](CCSC)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCCN)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@H](CSSC(=O)OCc1ccccc1)C(N)=O

nearest known ligand 0.64

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	CTSL	P07711	3/20	0.64

▸	CTSS	P25774	3/20	0.64

▸	CTSK	P43235	3/20	0.64

▸	CTSH	P09668	1/20	0.62

▸	C5AR1	P21730	2/20	0.59

▸	NMBR	P28336	2/20	0.58

▸	GRPR	P30550	2/20	0.58

▸	GLP1R	P43220	6/20	0.56

▸	GCGR	P47871	3/20	0.56

▸	MC4R	P32245	1/20	0.55

▸	MC5R	P33032	1/20	0.55

▸	MC3R	P41968	1/20	0.55

▸	MC1R	Q01726	1/20	0.55

▸	CXCL8	P10145	4/20	0.52

▸	CCKBR	P32239	2/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26426177	0.96	CTSL (0.64)	CTSLCTSSCTSKCTSHC5AR1
SCHEMBL25665363	0.94	CTSL (0.69)	CTSLCTSSCTSKCTSHC5AR1
SCHEMBL25664212	0.93	CTSL (0.68)	CTSLCTSSCTSKCTSHC5AR1
SCHEMBL25664225	0.92	CTSL (0.67)	CTSLCTSSCTSKCTSHC5AR1
SCHEMBL30439204	0.92	C5AR1 (0.66)	CTSLCTSSCTSKCTSHC5AR1
SCHEMBL25665234	0.91	CTSL (0.69)	CTSLCTSSCTSKCTSHC5AR1
SCHEMBL25664250	0.90	CTSL (0.65)	CTSLCTSSCTSKCTSHC5AR1
SCHEMBL25664294	0.89	CTSL (0.64)	CTSLCTSSCTSKCTSHC5AR1
SCHEMBL25664218	0.89	CTSL (0.64)	CTSLCTSSCTSKCTSHC5AR1
SCHEMBL26428433	0.88	CTSL (0.65)	CTSLCTSSCTSKCTSHC5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023069502-A2	PEPTIDE CONJUGATES AND THERAPEUTIC AGENTS HAVING IMPROVED PHARMACOLOGICAL AND PHARMACOKINETIC PROPERTIES	RESOLUTE BIO, INC. (US)	2023-04-27	—	—	WO	disclosed