SCHEMBL25664367

SCHEMBL25664367

CC1OCc2cc(Br)ccc2O1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.41
ADRA2A P08913 3/20 0.38
PNMT P11086 3/20 0.38
ADRA2B P18089 3/20 0.38
ADRA2C P18825 3/20 0.38
AHR P35869 3/20 0.36
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
BLM P54132 1/20 0.34
AKR1B1 P15121 1/20 0.34
BACE1 P56817 2/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
AR P10275 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GLS O94925 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28908423 0.75 ALDH1A1 (0.42) MAPTTDP1
SCHEMBL5809100 0.74 PBRM1 (0.60) PBRM1ADRA2APNMTADRA2BADRA2C
SCHEMBL29891564 0.74 PBRM1 (0.60) PBRM1ADRA2APNMTADRA2BADRA2C
SCHEMBL15724660 0.74 PBRM1 (0.60) PBRM1ADRA2APNMTADRA2BADRA2C
SCHEMBL4954350 0.73 NISCH (0.53) LMNAHTT
SCHEMBL2545956 0.72 AHR (0.50) PBRM1ADRA2APNMTADRA2BADRA2C
SCHEMBL2209905 0.72 AHR (0.50) PBRM1ADRA2APNMTADRA2BADRA2C
SCHEMBL2545960 0.72 AHR (0.50) PBRM1ADRA2APNMTADRA2BADRA2C
SCHEMBL17321070 0.71 PBRM1 (0.49) PBRM1ADRA2APNMTADRA2BADRA2C
SCHEMBL17233208 0.71 PBRM1 (0.49) PBRM1ADRA2APNMTADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4020081-B1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM, PATTERNING PROCESS, AND SILICON COMPOUND SHINETSU CHEMICAL CO (JP) 2023-05-17 EP disclosed