Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23726539 | 0.82 | NPC1 (0.43) | NPC1RAB9A | |
| SCHEMBL25664480 | 0.73 | NPC1 (0.38) | NPC1RAB9A | |
| SCHEMBL25664484 | 0.73 | NPC1 (0.39) | NPC1RAB9A | |
| SCHEMBL25664481 | 0.71 | NPC1 (0.46) | NPC1RAB9A | |
| SCHEMBL25664239 | 0.70 | DRD2 (0.33) | — | |
| SCHEMBL334839 | 0.69 | GLP1R (0.31) | — | |
| SCHEMBL30513555 | 0.67 | NPC1 (0.48) | NPC1RAB9A | |
| SCHEMBL20876602 | 0.67 | NPC1 (0.48) | NPC1RAB9A | |
| SCHEMBL10436530 | 0.66 | SLC6A4 (0.38) | NPC1RAB9A | |
| SCHEMBL23725138 | 0.65 | NPC1 (0.40) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143612-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143612-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | HAVCR2, HMBS, VHL | NPC1 165/4885RAB9A 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.