Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674996 | 0.82 | CHRNA7 (0.59) | CHRNA7AOC3KDM4EALDH1A1SLC6A2 | |
| Hydrochloric Acid SCHEMBL11332719 | 0.80 | CHRNA7 (0.56) | CHRNA7AOC3KDM4EALDH1A1SLC6A2 | |
| Bromide SCHEMBL10595079 | 0.80 | CHRNA7 (0.56) | CHRNA7AOC3KDM4EALDH1A1SLC6A2 | |
| Water SCHEMBL28355612 | 0.80 | CHRNA7 (0.56) | CHRNA7AOC3KDM4EALDH1A1SLC6A2 | |
| SCHEMBL31013838 | 0.76 | SLC6A2 (0.47) | ACP3AOC3ALDH1A1ACHETAAR1 | |
| SCHEMBL23429115 | 0.75 | ACP3 (0.44) | ACP3AOC3ALDH1A1TAAR1SLC6A2 | |
| SCHEMBL11604400 | 0.75 | ACP3 (0.55) | ACP3AOC3KDM4EALDH1A1ACHE | |
| SCHEMBL16363245 | 0.75 | ACHE (0.49) | ACP3AOC3ALDH1A1ACHEMAPT | |
| SCHEMBL19724322 | 0.75 | ACHE (0.49) | ACP3AOC3ALDH1A1ACHEMAPT | |
| SCHEMBL19122026 | 0.75 | ACHE (0.49) | ACP3AOC3ALDH1A1ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180424-A1 | SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS | BioCryst Pharmaceuticals, Inc. (US) | 2023-05-17 | — | — | EP | disclosed |