Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9967710 | 0.81 | GRM5 (0.46) | GRM5FFAR1CA12CA1CA2 | |
| SCHEMBL10254848 | 0.80 | GRM5 (0.45) | GRM5FFAR1CA12CA1CA2 | |
| SCHEMBL30469481 | 0.80 | GRM5 (0.69) | GRM5FFAR1CA12CA1CA2 | |
| SCHEMBL30469478 | 0.80 | GRM5 (0.69) | GRM5FFAR1CA12CA1CA2 | |
| SCHEMBL4562089 | 0.80 | GRM5 (0.69) | GRM5FFAR1CA12CA1CA2 | |
| SCHEMBL4946180 | 0.74 | GRM5 (0.62) | GRM5FFAR1CA12CA1CA2 | |
| SCHEMBL7132620 | 0.72 | GRM5 (0.59) | GRM5FFAR1CA12CA1CA2 | |
| SCHEMBL23704113 | 0.70 | ACHE (0.57) | GRM5FFAR1CA12CA1CA2 | |
| SCHEMBL28841296 | 0.69 | KCNH2 (0.59) | GRM5FFAR1CA12CA1CA2 | |
| SCHEMBL25128133 | 0.69 | GRM5 (0.56) | GRM5FFAR1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |