Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.69 |
| ▸ | ACHE | P22303 | 3/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30469481 | 1.00 | GRM5 (0.69) | GRM5ACHEFFAR1CA12CA1 | |
| SCHEMBL30469478 | 1.00 | GRM5 (0.69) | GRM5ACHEFFAR1CA12CA1 | |
| SCHEMBL4946180 | 0.93 | GRM5 (0.62) | GRM5ACHEFFAR1CA12CA1 | |
| SCHEMBL7132620 | 0.90 | GRM5 (0.59) | GRM5ACHEFFAR1CA12CA1 | |
| SCHEMBL23704113 | 0.87 | ACHE (0.57) | GRM5ACHEFFAR1CA12CA1 | |
| SCHEMBL29794004 | 0.87 | KCNH2 (0.59) | GRM5ACHEFFAR1CA12CA1 | |
| SCHEMBL10035460 | 0.87 | ALDH1A1 (0.64) | GRM5ACHEFFAR1CA12CA1 | |
| SCHEMBL28841296 | 0.87 | KCNH2 (0.59) | GRM5ACHEFFAR1CA12CA1 | |
| SCHEMBL25128133 | 0.87 | GRM5 (0.56) | GRM5ACHEFFAR1CA12CA1 | |
| SCHEMBL7670848 | 0.85 | GRM5 (0.55) | GRM5ACHEFFAR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292604-B1 | 2-AMINOCARBONYL-9H-PURINE DERIVATIVES | PFIZER LTD (GB) | 2009-05-13 | — | — | EP | claimed |
| US-4070333-A | AROMATIZATION CATALYST, ADDITION POLYMERIZATION | HERCULES INCORPORATED (US) | 1978-01-24 | — | — | US | claimed |
| WO-2023157909-A1 | METHOD FOR PRODUCING DIARYLACETYLENE DERIVATIVE | 関東電化工業株式会社 | 2023-08-24 | — | — | WO | disclosed |
| CN-109574818-B | Polysubstituted indanone derivative and preparation method thereof | 华侨大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-111333572-A | Method for synthesizing bisisoquinoline through double C-H activation/cyclization reaction | 桂林理工大学 | 2020-06-26 | — | — | CN | disclosed |
| CN-108484499-B | Method for preparing polysubstituted isoquinoline derivative from hydroxylamine and alkyne | 清华大学 | 2020-06-19 | — | — | CN | disclosed |
| CN-110330591-A | Porous organic polymer and its preparation method and application of the one kind containing Phosphine ligands | 青岛科技大学 | 2019-10-15 | — | — | CN | disclosed |
| US-9493494-B2 | Phosphinine oxide derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2016-11-15 | — | — | US | disclosed |
| US-20150344506-A1 | NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2015-12-03 | — | — | US | disclosed |
| EP-1113017-B1 | SILOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE SAME | CHISSO CORP (JP) | 2005-12-21 | — | — | EP | disclosed |
| US-6376694-B1 | Silole derivatives and organic electroluminescent element containing the same | CHISSO CORPORATION (JP) | 2002-04-23 | — | — | US | disclosed |
| US-4144218-A | MOLDING MATERIALS | HERCULES INCORPORATED (US) | 1979-03-13 | — | — | US | disclosed |
| EP-0000385-A1 | Thermosetting compositions based on polyarylacetylenes and substituted polyphenylene oxides and resins obtained by curing them | HERCULES INCORPORATED (US) | 1979-01-24 | — | — | EP | disclosed |
| US-4097460-A | DIPHENYLACETYLENE, DIPHENYLBUTADIYNE, MOLDING MATERIALS FOR HIGH TEMPERATURE APPLICATIONS | HERCULES INCORPORATED (US) | 1978-06-27 | — | — | US | disclosed |
| US-4070333-A | AROMATIZATION CATALYST, ADDITION POLYMERIZATION | HERCULES INCORPORATED (US) | 1978-01-24 | — | — | US | disclosed |
| US-4026859-A | AROMATIZATION CATALYST | HERCULES INCORPORATED (US) | 1977-05-31 | — | — | US | disclosed |
| US-4026860-A | AROMATIZATION CATALYST | HERCULES INCORPORATED (US) | 1977-05-31 | — | — | US | disclosed |
| US-4026861-A | AROMATIZATION CATALYST | HERCULES INCORPORATED (US) | 1977-05-31 | — | — | US | disclosed |
| US-3993711-A | THERMOSETTING RESINS; COUPLING AGENTS; CARBOXYLATED PREPOLYMER | HERCULES INCORPORATED (US) | 1976-11-23 | — | — | US | disclosed |
| US-3931093-A | CURING | HERCULES INCORPORATED (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344506-A1 | NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF | PHOSPHO1, PPIP5K2, ITPA | GRM5 732/4885ACHE 107/4885FFAR1 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.