SCHEMBL2566684

SCHEMBL2566684

N#CCCCCC(C#N)C(C#N)C#N

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
MAPT P10636 1/20 0.37
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22980647 0.98 TSHR (0.36) TSHRMAPTALDH1A1TDP1
SCHEMBL23388988 0.98 TSHR (0.36) TSHRMAPTALDH1A1TDP1
SCHEMBL23388975 0.98 TSHR (0.36) TSHRMAPTALDH1A1TDP1
SCHEMBL23388956 0.98 TSHR (0.36) TSHRMAPTALDH1A1TDP1
SCHEMBL23388981 0.92 TSHR (0.39) TSHRMAPTALDH1A1TDP1
SCHEMBL18116793 0.78 TSHR (0.41) TSHRMAPTALDH1A1TDP1
SCHEMBL17935684 0.73 TSHR (0.43) TSHRMAPTALDH1A1TDP1
SCHEMBL820231 0.71 TSHR (0.39) TSHRALDH1A1TDP1
SCHEMBL59340 0.71
SCHEMBL30678315 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333375-A1 CYANOCARBON COMPOSITIONS ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2025-10-30 US disclosed
US-12215070-B2 Cyanocarbon compositions ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2025-02-04 US disclosed
EP-4061795-A1 COMPOSITIONS COMPRISING TRISCYANOHEXANE Ascend Performance Materials Operations LLC (US) 2022-09-28 EP disclosed
CN-114555554-A Composition comprising hexanetricarbonitrile 奥升德功能材料运营有限公司 2022-05-27 CN disclosed
US-20210155579-A1 CYANOCARBON COMPOSITIONS ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2021-05-27 US disclosed
WO-2021102286-A1 COMPOSITIONS COMPRISING TRISCYANOHEXANE ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2021-05-27 WO disclosed
US-20160211553-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2016-07-21 US disclosed
EP-2382241-A2 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS Bridgestone Corporation (JP) 2011-11-02 EP disclosed
WO-2010085631-A2 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS BRIDGESTONE CORPORATION (JP) 2010-07-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12215070-B2 Cyanocarbon compositions CYCS, CBR3, PCCA TSHR 4133/4885MAPT 4098/4885ALDH1A1 3668/4885
US-20250333375-A1 CYANOCARBON COMPOSITIONS CYCS, CBR3, PCCA TSHR 4133/4885MAPT 4098/4885ALDH1A1 3668/4885
US-20210155579-A1 CYANOCARBON COMPOSITIONS CYCS, CBR3, PCCA TSHR 4133/4885MAPT 4098/4885ALDH1A1 3668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.