Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256660 | 0.84 | KCNH2 (0.39) | GRM5KCNH2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10254253 | 0.84 | MEN1 (0.39) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL22779054 | 0.80 | CHRM2 (0.39) | GRM5KCNH2CA12CA2CA9 | |
| SCHEMBL21258286 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL22779158 | 0.78 | CHRM2 (0.43) | GRM5KCNH2SMN1; SMN2 | |
| SCHEMBL2110164 | 0.74 | CA12 (0.43) | GRM5KCNH2CA12CA2CA9 | |
| SCHEMBL9967728 | 0.73 | GRM5 (0.40) | GRM5KCNH2CA12CA2CA9 | |
| SCHEMBL4457730 | 0.71 | GRM5 (0.64) | GRM5KCNH2CA12CA2CA9 | |
| SCHEMBL9445826 | 0.71 | GRM5 (0.64) | GRM5KCNH2CA12CA2CA9 | |
| SCHEMBL2110165 | 0.70 | CA12 (0.40) | GRM5KCNH2CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392096-A1 | COMPOUND ACTING AS ANTIBIOTICS | KBP BIOSCIENCES CO., LTD. (CN) | 2020-12-17 | — | — | US | disclosed |
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392096-A1 | COMPOUND ACTING AS ANTIBIOTICS | PEPD, NRDC, DPP4 | GRM5 4120/4885KCNH2 3488/4885CA12 2988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.