SCHEMBL256676

SCHEMBL256676

CCCC(F)(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5653717 0.82 CES2 (0.32)
SCHEMBL16144914 0.82 CES2 (0.32)
SCHEMBL15081202 0.79
SCHEMBL11918117 0.79
SCHEMBL4077275 0.78 CES2 (0.43)
SCHEMBL25815236 0.77
SCHEMBL22624129 0.76
SCHEMBL8375997 0.75
SCHEMBL13555443 0.75
SCHEMBL2002186 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022143262-A1 ENERGY STORAGE DEVICE 广东微电新能源有限公司 2022-07-07 WO claimed
WO-2024034522-A1 ADDITIVE FOR NON-AQUEOUS ELECTROLYTIC SOLUTION, NON-AQUEOUS ELECTROLYTIC SOLUTION, AND POWER STORAGE DEVICE 住友精化株式会社 2024-02-15 WO disclosed
US-20210093618-A1 SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF GENENTECH, INC. (US) 2021-04-01 US disclosed
US-9522906-B2 Tetrahydroquinoline analogues as muscarinic agonists ACADIA PHARMACEUTICALS, INC. (US) 2016-12-20 US disclosed
EP-2611300-B1 SUBSTITUTED ANNELATED DIHYDROPYRIMIDINONE COMPOUNDS BAYER IP GMBH (DE) 2016-04-06 EP disclosed
US-20140221364-A1 TETRAHYDROQUINOLINE ANALOGUES AS MUSCARINIC AGONISTS ACADIA PHARMACEUTICALS, INC. (US) 2014-08-07 US disclosed
CN-102471252-B Process for producing (fluoroalkylthio) acetic acid ester SUMITOMO CHEMICAL CO 2014-07-02 CN disclosed
CN-103709079-A Process for preparation of (fluoroalkylthio)acetic acid esters MASAJI HIROTA HIROYUKI MIYAZAKI TADAYOSHI ITOH 2014-04-09 CN disclosed
US-8680115-B2 Tetrahydroquinoline analogues as muscarinic agonists ACADIA PHARMACEUTICALS, INC. (US) 2014-03-25 US disclosed
EP-2684870-A1 METHOD FOR PREPARING THIOCARBOXYLIC ACID S-(FLUOROALKYL) ESTER Sumitomo Chemical Company Limited (JP) 2014-01-15 EP disclosed
CN-101027048-A Medicinal composition as immunosuppressant SANKYO CO (JP) 2007-08-29 CN disclosed
US-20070149597-A1 Medicinal composition as immunosuppressant SANKYO COMPANY, LIMITED (JP) 2007-06-28 US disclosed
EP-1782804-A1 MEDICINAL COMPOSITION AS IMMUNOSUPPRESSANT Sankyo Company, Limited (JP) 2007-05-09 EP disclosed
US-7160875-B2 Malonamide derivatives HOFFMANN-LA RACHE INC. (US) 2007-01-09 US disclosed
US-7160875-B2 Malonamide derivatives HOFFMANN-LA RACHE INC. (US) 2007-01-09 US disclosed
CN-1223561-C Compound having tetrahydronalphthalene skeleton and liquid crystal compsn. contg. same DAINIPPON INK & CHEMICALS (JP) 2005-10-19 CN disclosed
WO-2005023772-A1 MALONAMIDE DERIVATIVES BLOCKING THE ACTIVITY OF GAMA-SECRETASE F. HOFFMANN-LA ROCHE AG (CH) 2005-03-17 WO disclosed
CN-1356969-A Compound having tetrahydronalphthalene skeleton and liquid crystal compsn. contg. same DAINIPPON INK & CHEMICALS (JP) 2002-07-03 CN disclosed
CN-1075143-A Optically active azole compounds TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-08-11 CN disclosed
CN-1072680-A Optically active azole compounds and method for making thereof and purposes TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-06-02 CN disclosed