Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14767324 | 0.75 | — | — | |
| SCHEMBL14767322 | 0.73 | — | — | |
| SCHEMBL19230508 | 0.71 | HSP90AA1 (0.33) | — | |
| SCHEMBL24873946 | 0.66 | — | — | |
| SCHEMBL23638849 | 0.65 | PPARG (0.33) | — | |
| SCHEMBL24525250 | 0.63 | — | — | |
| SCHEMBL24873942 | 0.63 | — | — | |
| SCHEMBL14547649 | 0.62 | ALDH1A1 (0.35) | — | |
| SCHEMBL25668834 | 0.61 | ACLY (0.33) | — | |
| SCHEMBL23199051 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023100061-A1 | 3-PHENYL-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID DERIVATIVES AS BRANCHED-CHAIN ALPHA KETO ACID DEHYDROGENASE KINASE INHIBITORS FOR THE TREATMENT OF DIABETES, KIDNEY DISEASES, NASH AND HEART FAILURE | PFIZER INC. (US) | 2023-06-08 | — | — | WO | disclosed |