Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PIP5K1C | O60331 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIP5K1B | O14986 | 1/20 | 0.46 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27383392 | 0.90 | ALDH1A1 (0.58) | NAMPTALDH1A1CYP2C19ENPP3ENPP1 | |
| SCHEMBL29348790 | 0.84 | NAMPT (0.53) | NAMPTRAB9AMAPK10MAPK8MAPK14 | |
| SCHEMBL19639899 | 0.84 | MEN1 (0.55) | NAMPTALDH1A1NPC1RAB9APOLB | |
| SCHEMBL8278939 | 0.82 | NPSR1 (0.68) | ALDH1A1NPC1RAB9AMAPK10MAPK8 | |
| SCHEMBL31401961 | 0.82 | KMT2A (0.56) | NAMPTNPC1RAB9AMAPK10MAPK8 | |
| SCHEMBL7865123 | 0.81 | NAMPT (0.72) | NAMPTALDH1A1CYP2C19NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL435505 | 0.80 | NAMPT (0.70) | NAMPTALDH1A1CYP2C19NPC1RAB9A | |
| SCHEMBL1339196 | 0.78 | PTPN1 (0.71) | NAMPTALDH1A1CYP2C19NPC1RAB9A | |
| SCHEMBL7863859 | 0.78 | PTPN1 (0.66) | NAMPTALDH1A1CYP2C19RAB9AENPP3 | |
| SCHEMBL8363734 | 0.77 | PTPN1 (0.74) | NAMPTALDH1A1CYP2C19NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109883-A1 | AROMATIC HETEROCYCLE-SUBSTITUTED COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2023-06-22 | — | — | WO | disclosed |