Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28156554 | 0.98 | DPP7 (0.47) | DPP7EPHX1DNM1RRM1OPRM1 | |
| SCHEMBL28985254 | 0.95 | OPRM1 (0.46) | DPP7EPHX1RRM1OPRM1ALDH1A1 | |
| SCHEMBL27896530 | 0.95 | OPRM1 (0.46) | DPP7EPHX1RRM1OPRM1ALDH1A1 | |
| SCHEMBL28116311 | 0.95 | OPRM1 (0.46) | DPP7EPHX1RRM1OPRM1ALDH1A1 | |
| SCHEMBL28331825 | 0.95 | OPRM1 (0.46) | DPP7EPHX1RRM1OPRM1ALDH1A1 | |
| SCHEMBL9163909 | 0.95 | OPRM1 (0.46) | DPP7EPHX1RRM1OPRM1ALDH1A1 | |
| SCHEMBL28542120 | 0.95 | OPRM1 (0.46) | DPP7EPHX1RRM1OPRM1ALDH1A1 | |
| SCHEMBL27296396 | 0.95 | OPRM1 (0.46) | DPP7EPHX1RRM1OPRM1ALDH1A1 | |
| SCHEMBL9691923 | 0.95 | OPRM1 (0.46) | DPP7EPHX1RRM1OPRM1ALDH1A1 | |
| SCHEMBL28161008 | 0.95 | OPRM1 (0.46) | DPP7EPHX1RRM1OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107356-A1 | ANTIMALARIAL AGENTS | MERCK SHARP & DOHME LLC (US) | 2023-06-15 | — | — | WO | disclosed |