Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27199309 | 0.98 | TSHR (0.35) | TSHRPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL25671107 | 0.82 | TSHR (0.37) | TSHRPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL25671028 | 0.78 | AURKA (0.33) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| Hydrochloric Acid SCHEMBL27199544 | 0.77 | AURKA (0.32) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL27199404 | 0.74 | TSHR (0.34) | TSHRPKMKDM4EALDH1A1MAPK1 | |
| SCHEMBL22146201 | 0.71 | PKM (0.45) | TSHRPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3188011 | 0.70 | KDM4E (0.39) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL22146202 | 0.69 | PKM (0.51) | TSHRPKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL27199553 | 0.69 | GAA (0.39) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL25754662 | 0.69 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109120-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023108536-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |