Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22146147 | 0.85 | EPHB4 (0.36) | PKMPRKCZGRM2EPHB4LMNA | |
| SCHEMBL22146208 | 0.82 | TSHR (0.41) | PKMTSHRGRM2EPHB4LMNA | |
| SCHEMBL22146202 | 0.81 | PKM (0.51) | PKMTSHREPHB4LMNAPOLB | |
| SCHEMBL21915123 | 0.79 | GRIN2B (0.48) | PRKCZTSHRL3MBTL1 | |
| SCHEMBL30219956 | 0.79 | ALDH1A1 (0.40) | PRKCZTSHRLMNAPOLBMEN1 | |
| SCHEMBL18965059 | 0.79 | ALDH1A1 (0.40) | PRKCZTSHRLMNAPOLBMEN1 | |
| SCHEMBL18965057 | 0.79 | ALDH1A1 (0.38) | PRKCZPOLB | |
| SCHEMBL30220012 | 0.79 | ALDH1A1 (0.38) | PRKCZPOLB | |
| SCHEMBL18964711 | 0.78 | GRIN2B (0.40) | PRKCZPOLBMEN1KMT2A | |
| SCHEMBL30219973 | 0.78 | GRIN2B (0.40) | PRKCZPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386591-B1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | CADENT THERAPEUTICS INC (US) | 2020-06-24 | — | — | EP | disclosed |