SCHEMBL2567153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2567164	1.00	BACE1 (0.39)	BACE1CASP3FNTAFNTBTP53
	SCHEMBL4496034	0.89	CES1 (0.35)	BACE1CASP3RXFP1AURKBCA12
	SCHEMBL4494407	0.89	BACE1 (0.41)	BACE1CASP3TP53MAPTSMN1; SMN2
	SCHEMBL4496024	0.89	CES1 (0.35)	BACE1CASP3RXFP1AURKBCA12
	SCHEMBL4494396	0.89	BACE1 (0.41)	BACE1CASP3TP53MAPTSMN1; SMN2
	SCHEMBL3157920	0.87	BACE1 (0.42)	BACE1CASP3TP53MAPTSMN1; SMN2
	SCHEMBL5270139	0.84	BACE1 (0.46)	BACE1CASP3TP53MAPTSMN1; SMN2
	SCHEMBL480753	0.84	KMT2A (0.39)	BACE1TP53MAPTSMN1; SMN2RXFP1
	SCHEMBL20710161	0.84	BACE1 (0.46)	BACE1CASP3HPSEMEN1KMT2A
	SCHEMBL480541	0.82	RXFP1 (0.47)	CASP3TP53MAPTSMN1; SMN2RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.