Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28293668 | 0.91 | TDP1 (0.42) | MAPTALDH1A1TDP1PNMTGPR35 | |
| SCHEMBL7604948 | 0.90 | MAPT (0.47) | MAPTALDH1A1TDP1PNMTGPR35 | |
| Quinoline SCHEMBL28062786 | 0.84 | POLB (0.49) | MAPTALDH1A1TDP1LMNAHTT | |
| SCHEMBL2061513 | 0.81 | PNMT (0.50) | MAPTALDH1A1TDP1PNMTGPR35 | |
| SCHEMBL7581608 | 0.78 | PARP1 (0.57) | MAPTTDP1LMNAHTTKMT2A | |
| Indoline SCHEMBL27976781 | 0.77 | ALDH1A1 (0.51) | MAPTALDH1A1TDP1PNMTTSHR | |
| SCHEMBL9501421 | 0.76 | TDP1 (0.45) | MAPTALDH1A1TDP1PNMTGPR35 | |
| SCHEMBL31357065 | 0.76 | TDP1 (0.45) | MAPTALDH1A1TDP1PNMTGPR35 | |
| SCHEMBL1126861 | 0.76 | MAPT (0.43) | MAPTALDH1A1TDP1PNMTTSHR | |
| SCHEMBL8805931 | 0.76 | PNMT (0.44) | MAPTALDH1A1TDP1PNMTGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109928972-A | A kind of matrine derivative and its application in drug | 中国医学科学院药用植物研究所 | 2019-06-25 | — | — | CN | claimed |
| CN-109761874-A | Preparation process of medical intermediate 4-nitroindole | 代可昕 | 2019-05-17 | — | — | CN | claimed |
| CN-105622483-B | A kind of synthetic method of 4- nitroindoline | 苏州艾缇克药物化学有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-109053534-A | A kind of preparation method of medicine intermediate 4- nitroindoline | 苏州盖德精细材料有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-106319956-B | A kind of carboxymethyl cellulose wrap dressing agent containing 4- nitroindolines | 嘉兴市新飞腾塑业有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-106892853-A | The method that 4- nitroindolines or 5- nitroindoline catalytic hydrogenations prepare amino indole | 甘肃中科药源生物工程股份有限公司 | 2017-06-27 | — | — | CN | claimed |
| CN-106319956-A | Carboxymethylcellulose warp yarn sizing agent containing 4-nitroindole | 朱玲 | 2017-01-11 | — | — | CN | claimed |
| CN-106243010-A | A kind of preparation method of 4 nitroindolines | 叶芳 | 2016-12-21 | — | — | CN | claimed |
| CN-106232834-A | Sample preparation methods | 牛津纳米孔技术公司 | 2016-12-14 | — | — | CN | claimed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | claimed |
| CN-105705656-A | Method of producing a composite material | 牛津纳米孔技术公司 | 2016-06-22 | — | — | CN | claimed |
| CN-105622484-A | 4-nitroindole and preparation method thereof | YE FANG | 2016-06-01 | — | — | CN | claimed |
| CN-105622483-A | Synthesis method of 4-nitroindole | ITIC MEDCHEM CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-105017215-A | Method for preparing functional isoquinoline | SHANGHAI INST TECHNOLOGY | 2015-11-04 | — | — | CN | claimed |
| CN-103420895-A | Preparation method of 4-aminoindole | ASCEPION PHARMACEUTICALS INC | 2013-12-04 | — | — | CN | claimed |
| CN-103351326-A | Synthesis process of important pharmaceutical chemical intermediate 4-nitroindole | ZHANGJIAGANG WEISHENG BIOLOG PHARCEUTICAL CO LTD | 2013-10-16 | — | — | CN | claimed |
| CN-101823992-A | Preparation method of 4-nitroindole | CHENGYUN ZHOU | 2010-09-08 | — | — | CN | claimed |
| CN-101072882-A | Methods for long-range sequence analysis of nucleic acids | SEQUENOM INC (US) | 2007-11-14 | — | — | CN | claimed |
| EP-4638441-A1 | GLYCINE DERIVATIVES WITH P2X4 RECEPTOR-BLOCKING ACTIVITY AS DIAGNOSTICS AND FOR THE TREATMENT OF PAIN, INFLAMMATION, CANCER, AND OTHER P2X4 RECEPTOR-RELATED DISEASES | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2025-10-29 | — | — | EP | disclosed |
| CN-1035521-A | The preparation method of indigo compound | MITSUI TOATSU CHEMICALS (JP) | 1989-09-13 | — | — | CN | disclosed |