Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.44 |
| ▸ | FGF1 | P05230 | 3/20 | 0.44 |
| ▸ | FGF2 | P09038 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16092453 | 0.94 | MAPK1 (0.55) | GJB2MAPK1MMP13 | |
| SCHEMBL4298713 | 0.94 | MAPK1 (0.55) | GJB2MAPK1MMP13 | |
| SCHEMBL14506448 | 0.94 | MAPK1 (0.55) | GJB2MAPK1MMP13 | |
| SCHEMBL30391777 | 0.92 | MAPK1 (0.53) | GJB2MAPK1MMP13 | |
| SCHEMBL18392190 | 0.91 | MAPK1 (0.58) | GJB2MAPK1HPSEFGF1FGF2 | |
| SCHEMBL16092454 | 0.91 | GJB2 (0.54) | GJB2MAPK1MMP13HPSEFGF1 | |
| SCHEMBL16502213 | 0.89 | MMP13 (0.49) | GJB2MAPK1MMP13HPSEFGF1 | |
| SCHEMBL16092085 | 0.88 | GJB2 (0.43) | GJB2MMP13 | |
| SCHEMBL19841394 | 0.87 | CD209 (0.51) | GJB2MAPK1MMP13HPSEFGF1 | |
| SCHEMBL12972816 | 0.87 | GJB2 (0.58) | GJB2MAPK1MMP13HPSEFGF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091441-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A TETRA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | MERCK SHARP & DOHME LLC (US) | 2023-05-25 | — | — | WO | disclosed |