Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16539175 | 0.78 | KDM4E (0.48) | L3MBTL1KDM4EPOLBTSHRHSD17B10 | |
| SCHEMBL16627207 | 0.76 | NPC1 (0.53) | L3MBTL1KDM4EPOLBALDH1A1NPC1 | |
| SCHEMBL25196067 | 0.76 | ALPL (0.62) | HSD17B10ALDH1A1MEN1KMT2AHDAC3 | |
| SCHEMBL17279784 | 0.76 | RAB9A (0.62) | KDM4EPOLBLMNAALDH1A1NPC1 | |
| SCHEMBL15425080 | 0.76 | MAPT (0.58) | KDM4EPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL13140980 | 0.76 | MAPT (0.50) | KDM4EPOLBLMNAALDH1A1NPC1 | |
| SCHEMBL11005422 | 0.75 | PDE4A (0.72) | KDM4EPOLBTSHRLMNAHSD17B10 | |
| SCHEMBL15425084 | 0.74 | APP (0.46) | KDM4EPOLBTSHRHSD17B10ALDH1A1 | |
| SCHEMBL15425101 | 0.74 | MAPT (0.48) | KDM4EPOLBTSHRHSD17B10ALDH1A1 | |
| SCHEMBL25196239 | 0.74 | MAPT (0.67) | L3MBTL1POLBLMNAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023089632-A1 | PYRAZOLE AMIDE BASED COMPOUNDS AND USES AGAINST BREAST CANCER THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-05-25 | — | — | WO | disclosed |