Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870086 | 0.85 | ALDH1A1 (0.45) | KDM4EALDH1A1NPSR1TSHRRXFP1 | |
| SCHEMBL25370118 | 0.83 | PIK3CA (0.48) | KDM4EALDH1A1NPSR1TSHRRXFP1 | |
| SCHEMBL31705502 | 0.79 | ALDH1A1 (0.46) | KDM4EALDH1A1NPSR1TSHRRXFP1 | |
| SCHEMBL29234849 | 0.78 | LIPG (0.52) | KDM4EALDH1A1NPSR1TSHRKMT2A | |
| SCHEMBL1440788 | 0.75 | ALDH1A1 (0.53) | KDM4EALDH1A1NPSR1TSHRKMT2A | |
| SCHEMBL4092425 | 0.74 | SCD (0.74) | — | |
| SCHEMBL31704539 | 0.74 | ALDH1A1 (0.36) | KDM4EALDH1A1NPSR1RXFP1MAPT | |
| SCHEMBL3151430 | 0.72 | CA1 (0.49) | TSHRCA1CA2NLRP3 | |
| SCHEMBL2944365 | 0.71 | SCD (0.46) | — | |
| SCHEMBL20305423 | 0.71 | CA1 (0.43) | KDM4EALDH1A1NPSR1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081441-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2023-05-11 | — | — | WO | disclosed |